Fenbendazole capsules are safe to use in most horses, as long as you follow the label directions. This medication kills parasites in a few days, and most horses can be safely turned out right after treatment is complete. Some horses may need to be monitored for a few more days as the fecal parasite counts come down, or in case they develop an allergic reaction to the medication. If your horse is treated with fenbendazole, you should not feed them grass or other greens as this will prevent the drug from doing its job.
Scientists at the National Centre for Human Genome Studies and Research at Panjab University have found that a broad-spectrum antiparasitic drug used in veterinary medicine, fenbendazole, could also be useful against certain cancers. The researchers investigated the effect of fenbendazole on 5-fluorouracil (FU)-resistant colorectal cancer cells and found that the compound increased cell death and blocked tumor growth.
The team investigated the effects of fenbendazole on different cell death pathways, and observed that the drug significantly increases apoptosis and G2/M phase arrest in FU-resistant cells compared to wild-type cells. It also significantly decreases tumor vascularity and promotes mitochondrial dysfunction in FU-resistant cells.
Currently, fenbendazole is a widely used and effective broad-spectrum anthelmintic in dogs and cats for gastrointestinal parasites such as roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not Dipylidium caninum, the common dog tapeworm), pinworms, hydatid cysts, ascarids, and most cestodes. It is also highly efficacious against the trematodes Heterobilharzia americana, Nanophyetus salmincola, and Paragonimus kellicotti16-21 in sheep and goats, as well as the cestodes Mesocestoides spp and Taenia spp in freshwater shrimp tanks.